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Updated: Jul 15, 2026

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution
13:47

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

Published on: February 24, 2015

呼吸道MMP-12和COPD中的DNA甲基化:一种综合性方法

Jonas Eriksson Ström1, Simon Kebede Merid2, Robert Linder3

  • 1Department of Public Health and Clinical Medicine, Section of Medicine, Umeå University, 901 87, Umeå, Sweden. jonas.eriksson.strom@umu.se.

Respiratory research
|January 10, 2025
PubMed
概括

慢性阻塞性肺病 (COPD) 涉及改变矩阵金属蛋白酶 (MMP) 调节,可能通过DNA甲基化. 这项研究揭示了COPD中MMP-12的表观遗传破坏,受遗传学和环境因素的影响.

关键词:
支气管镜检查 (bronchoscopy) 是一种用来检查支气管的方法.慢性阻塞性肺病 (COPD) 是一种慢性阻塞性肺病.通过DNA甲基化.细胞外基质改造的细胞外基质改造矩阵金属蛋白酶 (MMPs) 是一种多种组合的多种组合.

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