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相关概念视频

MicroRNAs01:22

MicroRNAs

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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
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RNA Interference01:23

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RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...
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Experimental RNAi02:15

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RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing its transcription or activating the RNA degradation process. The mechanism was discovered by Andrew Fire and Craig Mello in 1998 in plants. Today, it is observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals. This precise cellular mechanism of gene silencing has been developed into a technique that provides an efficient way to identify and determine the...
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Types of RNA01:23

Types of RNA

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Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
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siRNA - Small Interfering RNAs02:30

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Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
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Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches bind directly to a metabolite and can form unique stem-loop or hairpin structures in response to the amount of the metabolite present. They have two distinct regions – a metabolite-binding aptamer and an expression platform.
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相关实验视频

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Potato Virus X-Based microRNA Silencing VbMS In Potato.
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微RNA在调节米病原体相互作用中的作用

Yanfeng Jia1, Kai Wei1, Jiawang Qin1

  • 1Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.

Plants (Basel, Switzerland)
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PubMed
概括
此摘要是机器生成的。

米微RNA (miRNA) 是植物免疫力对抗主要病原体的关键调节者,如Magnaporthe oryzae,Xanthomonas oryzae和Rhizoctonia solani. 了解osa-miRNA功能有助于开发抗疾病的米品种.

关键词:
马格纳波特花 (Magnaporthe oryzae) 是一个很大的植物.这种植物是Rhizoctonia solani.克桑托莫纳斯里扎 (Xanthomonas oryzae pv.) 是一个植物. 一个叫做"Oryzae"的微RNAs 是一个微型RNA.米米饭 米饭 米饭 米饭.

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相关实验视频

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科学领域:

  • 植物分子生物学 植物分子生物学
  • 农业科学 农业科学
  • 生物化学 生物化学

背景情况:

  • 面临着由病原体Magnaporthe oryzae (M. oryzae),Xanthomonas oryzae pv. 引起的重大威胁. (Xoo) 和Rhizoctonia solani (R. solani),影响了粮食安全.
  • 植物,包括大米,拥有复杂的分子机制来防御各种病原体.
  • 植物微RNA (miRNA) 是基因表达的关键调节者,并且已经成为植物病原体相互作用的关键参与者.

研究的目的:

  • 总结一下最近在理解米饭中微RNA介导的免疫信号传递方面的进展.
  • 阐明大米中osa-miRNAs对特定病原体免疫力的功能和分子机制.
  • 要突出osa-miRNAs在米对M. oryzae,Xoo和R. solani.的反应中的作用.

主要方法:

  • 关于大米免疫和微RNA调节的当前科学文献的综述.
  • 基于osa-miRNA介导的基因表达调制 (转录后和转录后) 的分子机制的分析.
  • 专注于对特定的病原体的osa-miRNA反应:M. oryzae,Xoo和R. solani.

主要成果:

  • Osa-miRNAs通过mRNA裂变,转化抑制和潜在的DNA甲基化来调节基因表达.
  • 已经确定了特定的osa-miRNAs,它们在防治M. oryzae,Xoo和R. solani的米防御中发挥着关键作用.
  • 这些miRNAs是大米免疫信号通路的组成部分.

结论:

  • Osa-miRNAs对于协调大米对主要农业病原体的免疫是至关重要的.
  • 对osa-miRNA功能的进一步研究可能会导致开发新的策略来培育抗病米.
  • 了解这些分子机制对于提高大米作物的弹性和全球粮食安全至关重要.