后COVID-19对围产期结果的影响.
Gaukhar Kurmanova1, Ardak Ayazbekov2, Almagul Kurmanova1
1Medicine and Healthcare Faculty, Al Farabi Kazakh National University, 71, Al-Farabi Avenue, 050040 Almaty, Kazakhstan.
Diagnostics (Basel, Switzerland)
|January 11, 2025
概括
在孕妇中,无症状的COVID-19病史与不良妊娠结果有关. 这些包括胎盘异常和橄水,导致围产期结果差.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 围产儿医学 围产儿医学
背景情况:
- 怀有SARS-CoV-2感染的怀孕与流产,产前,早产和死产等不良结果有关.
- 怀孕期间之前的冠状病毒感染的长期影响仍在调查中.
研究的目的:
- 确定具有无症状COVID-19病史的妇女怀孕和分娩的临床特征.
- 评估过去无症状冠状病毒疾病2019对孕产妇和胎儿健康的影响.
主要方法:
- 一项在2021年8月至9月期间在哈萨克斯坦进行的比较研究.
- 招募了229名孕妇:133名孕妇有COVID-19病史 (暴露),96名孕妇没有 (未暴露).
- 分析了关于怀孕过程和分娩结果的临床数据.
主要成果:
- 在COVID-19的病史和橄水症 (φ = 0.743,p < 0.001) 之间发现了强烈的关联.
- 观察到中等强度的关联与贫血 (φ = 0.254,p < 0.001),异常的胎盘发育 (φ = 0.254,p < 0.011),带纠 (φ = 0.343,p = 0.000),低出生体重 (φ = 0.356,p < 0.001) 和死胎 (φ = 0.293,p < 0.001).
结论:
- 孕妇过去的COVID-19感染对胎盘发育和羊水量有持久的影响.
- 这些条件有助于产生不良的围产期结果,强调需要监测COVID-19后怀孕.
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