相关实验视频
Updated: Jun 3, 2025

07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
294
全血细胞计数参数比率的预后价值在急性肺栓塞中
Aynur Yurtseven1, Kerem Ensarioğlu2
1Department of Emergency Medicine, Ankara Etlik State Hospital, Ankara 06170, Turkey.
Diagnostics (Basel, Switzerland)
|January 11, 2025
概括
像中性粒细胞与淋巴细胞比率 (NLR) 和平均血小板体积与淋巴细胞比率 (MPVLR) 这样的炎症标志物可以帮助预测肺栓塞 (PE) 的结果. 在PE患者中,NLR显示了与住院时间和死亡率的最强相关性.
科学领域:
- 心脏病学 心脏病学
- 血液学 血液学 血液学
- 关键护理医学 关键护理医学
背景情况:
- 急性肺栓塞 (PE) 是心血管死亡的一个重要原因.
- 准确的风险分层对于管理PE患者至关重要.
- 传统的风险评估工具在预测准确性和成本方面存在局限性.
研究的目的:
- 调查PE患者炎症和凝固标志物的预后价值,特别是中性粒细胞与淋巴细胞的比率 (NLR),血小板与淋巴细胞的比率 (PLR) 和平均血小板体积与淋巴细胞的比率 (MPVLR).
- 评估这些标志物与风险分层和临床结果的关联.
主要方法:
- 对231名成年PE患者的回顾性分析.
- 排除患有感染,自身免疫性疾病或免疫抑制治疗的患者.
- 从常规血液计数计算NLR,PLR和MPVLR的计算.
- 通过sPESI定义的低风险和高风险群体之间的标记水平的比较.
主要成果:
- 与低风险患者相比,高风险PE患者的NLR和MPVLR显著更高.
- 升高的NLR,PLR和MPVLR与增加的ICU入院,输管和死亡率相关.
- NLR与住院时间和死亡率的关联最强,而PLR和MPVLR对整体住院的预测能力较低.
结论:
- NLR,MPVLR和PLR是具有成本效益的标志物,可以增强PE风险分层.
- NLR表现出最强大的预后值,与多种不良临床结果相关.
- 需要进一步的多中心研究来验证这些发现,并确定临床效用.
相关概念视频
Pneumonia III: Complications and Assessment
156
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
156
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
96
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
96

