胃腺癌偶尔通过PET/CT用PSMA带检测到的胃腺癌
Cesare Michele Iacovitti1, Barbara Muoio2, Marco Cuzzocrea1
1Division of Nuclear Medicine, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.
用-68 (Ga) 前列腺特异性膜抗原 (Ga-PSMA-11) 进行正子发射断层扫描/计算机断层扫描 (PET/CT) 可以揭示出意想不到的胃食道结腺癌. 这一案例凸显了评估PSMA PET/CT扫描中偶然发现的重要性.
科学领域:
- 核医学成像技术 核医学成像技术
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
背景情况:
- 前列腺特异性膜抗原 (PSMA) PET/CT 是诊断前列腺癌的宝贵工具.
- 对PSMA PET/CT的偶然发现需要仔细评估.
- 胃食道结腺癌可以作为偶然发现.
研究的目的:
- 报告一种由[68Ga]Ga-PSMA-11 PET/CT检测到的偶然的胃食道结腺癌病例.
- 强调评估胃中意外吸收的标记剂的重要性.
- 突出PSMA PET/CT在识别非前列腺相关恶性瘤方面的潜力.
主要方法:
- 一名患有高风险前列腺癌的74岁男性通过Ga-PSMA-11 PET/CT进行了分期.
- 图像检测显示前列腺中强烈的标记物吸收,在腹腔区域的病变中中度吸收.
- 结核区域病变的活检证实了Siewert型III胃食道结腺癌.
主要成果:
- 在前列腺中观察到大量的标记物吸收,与前列腺癌一致.
- 胃旁边的一个4厘米的病变显示Ga-PSMA-11的摄取量中等.
- 组织病理学证实HER2阴性,PDL-160%胃食道结腺癌.
结论:
- 在胃中偶然的Ga-PSMA-11吸收可能表明胃食道结腺癌.
- 除了前列腺癌之外,PSMA PET/CT可能在检测其他瘤病变方面发挥作用.
- 放射科医生和核医学医生应对PSMA PET/CT的偶然发现保持警.
更多相关视频
06:54MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
Published on: September 3, 2013
08:55A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
Published on: April 17, 2019
相关概念视频
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
