高饮食对治疗高血压患者的食后血管影响
Daniela Malta1, Sam Esfandiari2,3, Livia A Goldraich4
1School of Nutrition, Toronto Metropolitan University, 350 Victoria St., Toronto, ON M5B 2K3, Canada.
Nutrients
|January 11, 2025
概括
在高血压患者中,单次高食物并没有急剧改善血管功能. 这表明,饮食中的和较低的血压之间的联系是复杂的,不仅仅是由于对内皮功能的直接影响.
科学领域:
- 心血管研究研究心血管研究
- 营养科学 营养科学
- 高血压管理 高血压管理
背景情况:
- 饮食中的摄入量与血压相反相关.
- 可以通过增强内皮依赖放松来改善血压.
- 以前对健康个体的补充和血管功能进行的研究 yielded variable results. 之前对健康个体的补充和血管功能进行的研究产生了不同的结果.
研究的目的:
- 为了研究高食对食后内皮功能的急性影响.
- 在高血压患者中使用流媒扩张 (FMD) 评估内皮功能.
主要方法:
- 调查者盲目的随机交叉试验涉及33名接受治疗的高血压患者.
- 参与者摄入高 (~2400毫克) 和低 (~543毫克) 的食物.
- 内皮功能 (FMD) 在餐前和餐后60分钟和120分钟被测量.
主要成果:
- 在基线时或在高和低餐之间餐后60分钟内,口和口病没有显著差异.
- 在高食后120分钟食后出现更高口病的趋势 (p=0.07).
- 辐射动脉直径或饭之间血流没有显著差异.
结论:
- 治疗高血压患者中,单次高食物并没有显著改善血管功能.
- 这些发现不支持急性,单餐介导的内皮功能改善的假设.
- 饮食摄入量,内皮功能和降低血压之间的复杂关系需要进一步研究.
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