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益生菌:预防和管理心血管疾病的潜在策略
Anallely López-Yerena1, Victoria de Santisteban Villaplana1,2, Lina Badimon1,3,4
1Institut Recerca Sant Pau, Sant Quinti 77-79, 08041 Barcelona, Spain.
益生菌在控制胆固醇和血压等心血管风险因素方面表现有前途. 需要进一步的研究,以优化它们用于心血管疾病预防和管理的使用.
科学领域:
- 心血管健康 心血管健康
- 微生物组研究 微生物组研究
- 营养科学 营养科学
背景情况:
- 心血管疾病 (CVD) 仍然是全球主要的死亡原因.
- 新兴研究表明,益生菌可能会影响关键的心血管风险因素.
- 了解益生菌在预防心血管疾病中的确切作用至关重要.
研究的目的:
- 审查有关益生菌消费及其对主要心血管风险因素的影响的科学证据.
- 检查益生菌对特定人群的影响,包括高血压患者,II型糖尿病患者,代谢综合征患者,高胆固醇血症患者和冠状动脉疾病患者.
- 确定影响益生菌对心血管健康有效性的因素.
主要方法:
- 人类研究的综合文献综述.
- 对人类测量,炎症标志物,血压,葡萄糖代谢,脂质概况和内皮功能数据的分析.
- 基于益生菌特征和参与者个人资料的研究结果变异性的评估.
主要成果:
- 益生菌消费与对几种心血管风险标志物的积极影响有关.
- 观察到的好处包括改善血压,脂质概况和炎症.
- 结果的显著变化需要仔细考虑益生菌类型,剂量和输送.
结论:
- 益生菌代表了预防和管理心血管疾病的可行策略.
- 最佳的益生菌菌株,剂量,持续时间,输送媒介和性别特异性需要进一步调查.
- 将益生菌纳入健康的生活方式可能有助于心血管健康.
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