孕产妇长链多不和脂肪酸在怀孕中的状况和新生儿的身体组成
Mira Dewi1,2, Nuri Andarwulan2,3, Utami Wahyuningsih4
1Faculty of Medicine, IPB University, IPB Dramaga Campus, Bogor 16680, West Java, Indonesia.
Nutrients
|January 11, 2025
概括
在印度尼西亚,孕妇在怀孕期间摄入的DHA和EPA等长链多不和脂肪酸 (LC-PUFA) 不足. 较低的DHA摄入量与降低的出生体重相关,而较高的EPA和DHA水平显示出与婴儿身体组成的积极关联.
科学领域:
- 母婴营养 母婴营养
- 营养生物化学 营养生物化学
- 公共卫生 公共卫生
背景情况:
- 母亲的n-3PUFA状态与胎儿发育有关,但印度尼西亚的数据很少.
- 这项研究调查了印尼孕妇和新生儿的LC-PUFA摄入量和状态.
- 它探讨了母亲摄入量,生物标志物和婴儿身体组成之间的关联.
研究的目的:
- 为了评估印度尼西亚博戈尔的孕妇的长链多不和脂肪酸 (LC-PUFA) 饮食摄入量.
- 检查母亲的LC-PUFA摄入量与其在母亲血液,带血液和母乳中的水平之间的关系.
- 调查母亲和婴儿LC-PUFA水平与婴儿身体组成之间的关联.
主要方法:
- 142名孕妇和104名新生儿参与了这项研究.
- 通过24小时回忆和FFQ评估的能量,宏观营养素和LC-PUFA (LA,ALA,EPA,DHA) 的饮食摄入量.
- 在母体血液,带血液和母乳中测量LC-PUFA水平;新生儿的身体成分通过人体测量来确定.
主要成果:
- 能量,蛋白质和碳水化合物摄入不足的高患病率.
- 摄入的ALA,EPA和DHA显著低于推水平.
- 母亲的DHA摄入量与出生体重和婴儿脂肪量有负相关性;总脂肪和LA摄入量与新生儿脂肪积累增加有关.
- 母亲血液的EPA与婴儿脂肪质量%相关;带血液的DHA与新生儿出生体重相关.
结论:
- 在这个印度尼西亚人群中,母亲摄入关键的LC-PUFA不足.
- 饮食和生物标志物LC-PUFA水平与婴儿出生体重和身体组成有复杂的关联.
- 建议对印尼的母婴营养进行长度研究和有针对性的干预措施.
相关概念视频
03:38Structure of Lipids
86.5K
Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic...
86.5K
01:20Pathophysiology of Diabetes
860
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
860
01:25Blood Studies for Cardiovascular System III: Serum Lipid Profile
130
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
130
01:29Cholesterol: Significance and Regulation
500
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
500
01:31Lipid-derived Compounds in the Human Body
4.3K
Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
4.3K
01:28Overview of Fatty Acid Metabolism
30.2K
Lipids also are sources of energy that power cellular processes. Like carbohydrates, lipids are composed of carbon, hydrogen, and oxygen, but these atoms are arranged differently. Most lipids are nonpolar and hydrophobic. Major types include fats and oils, waxes, phospholipids, and steroids.
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
30.2K