结核病的临床表现:意大利单一中心的经验
Chiara Maria Trovato1, Francesca Ferretti1, Anna Pia Delli Bovi2
1Nutritional Rehabilitation Unit, Bambino Gesù Children Hospital IRCCS, 00165 Rome, Italy.
Nutrients
|January 11, 2025
概括
意大利的儿科乳病 (CeD) 诊断正在上升. 近年来,非经典的CeD症状增加了,如胀气和腹痛,严重的腹危机较少.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 免疫学 免疫学 免疫学
- 临床医学 临床医学
背景情况:
- 意大利儿童的乳病 (CeD) 患病率超过1.5%,并且在过去25年中呈现出持续增长.
- CeD的临床表现是多样化的,并且已经演变,最近观察到最初症状的变化.
研究的目的:
- 在12年的时间内分析儿科腹腔疾病临床表现的变化模式.
- 描述在意大利单一中心诊断出CeD的儿童的症状和诊断趋势的演变.
主要方法:
- 罗马Bambino Gesù儿童医院儿科CeD诊断的回顾性分析 (2011年3月至2023年6月).
- 患者被分为三组,大约为4年,以评估随时间的变化.
- 排除在其他地方先前 CeD 诊断的患者.
主要成果:
- 在排除后,总共有3396名儿童被纳入分析.
- 在研究期间,每年CeD诊断增加了17.5%.
- 观察到非经典的CeD形式 (胀气,腹痛) 的显著增加 (p=0.000064),同时危机的显著减少 (p<0.0001).
结论:
- 儿童每年被诊断患有乳病的人数有所增加.
- 结核病的临床表现已经转向非经典形式,严重结核病危机的发生有所减少.
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