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在MASLD中 Sarcopenia-Eat以击败肥胖症,移动以证明自己的力量

Dana Crişan^1,2, Lucreţia Avram^1,2, Andreea Morariu-Barb^1,3

¹Faculty of Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

|January 11, 2025

概括

肉症或肌肉损失在代谢功能障碍相关的脂肪性肝病 (MASLD) 中很常见. 了解它们的双向联系以及优化饮食,运动和减肥手术等治疗方法对于患者护理至关重要.

科学领域:

肝病学和老年病学肝病学和老年病学
代谢和营养障碍代谢和营养障碍

背景情况:

标志着与年龄相关的肌肉质量和力量丧失的萨科佩尼亚,与2型糖尿病 (T2DM) 和代谢综合征 (MetS) 等慢性疾病一起越来越多地得到认可.
与代谢功能障碍相关的脂肪性肝病 (MASLD) 经常与肉症共存,但这种关联往往被忽视,使患者管理复杂化.
新出现的证据表明,MASLD和肉症之间存在复杂的,双向的相互作用,这表明共享的病理生理机制.

研究的目的:

综合回顾萨科佩尼亚和MASLD之间的复杂关系.
阐明当前治疗策略和新发现,用于管理MASLD患者的肉症.
突出治疗肉症的挑战,特别是在肥胖和MASLD管理的背景下.

主要方法:

文献综述综合了关于肉病和MASLD的实验和临床发现.
分析当前和潜在的治疗干预措施,包括药理学,生活方式和外科手术方法.
检查减肥干预措施,如减肥手术,对MASLD中肉症的影响.

主要成果:

维生素D,丸激素和某些药物疗法显示出缓解肉症的潜力,但缺乏治疗共识.
包括饮食和炼在内的生活方式干预措施对于管理MASLD.中sarcopenic肥胖症至关重要.
腹腔外科手术对MASLD和代谢健康有好处,但对缩症有复杂的,尚未完全理解的影响.

结论:

MASLD和肉症之间的双向关系需要综合管理方法.
在MASLD患者中有效的治疗策略仍然是需要进一步研究和临床共识的领域.
解决被忽视的肉症对于改善MASLD患者和相关代谢疾病患者的治疗结果至关重要.

关键词:

马斯尔德马斯尔德是什么意思代谢综合征代谢综合征这种类型的麻症是sarcopenia.萨尔科佩尼克肥胖症肥胖症 2 型糖尿病 2 型糖尿病

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