胃癌外科治疗的进化 腹膜转移的外科治疗
Matthew Krell1, Suedeh Ranjbar1, Saige Gitlin1
1Department of Surgery, Division of Surgical Oncology, NYU Langone Health, NYU Grossman Long Island School of Medicine, Mineola, NY 11501, USA.
Cancers
|January 11, 2025
概括
腹膜转移 (PM) 的胃癌的结果不好. 腹腔内 (IP) 疗法,如加热腹腔内化疗 (HIPEC) 和加压气溶化疗 (PIPAC),在治疗这种晚期癌症方面表现有前途.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 胃癌 (GC) 是全球癌症死亡的主要原因.
- 腹转移 (PM) 显著恶化GC预后,生存时间有限.
- 目前的全身治疗,向疗法和免疫疗法在很大程度上对GC/PM无效.
研究的目的:
- 审查胃癌中腹膜转移的进展情况.
- 探索GC/PM的不断发展的治疗策略.
- 检查内 (IP) 治疗GC/PM的进展和结果.
主要方法:
- 文献综述侧重于GC中腹膜转移的发展.
- 对GC/PM的当前和新兴治疗方式的分析.
- 评估腹腔内疗法,包括加热腹腔内化疗 (HIPEC) 和加压腹腔内气溶化疗 (PIPAC).
主要成果:
- 腹膜转移在胃癌管理中是一个重大挑战.
- 由于全身治疗的局限性,腹膜内疗法正在引起人们的兴趣.
- HIPEC和PIPAC代表着IP治疗策略的不断发展,结果各不相同.
结论:
- 腹腔内疗法为治疗腹腔转移的胃癌提供了一个有前途的途径.
- 对HIPEC和PIPAC的进一步研究对于优化GC/PM治疗至关重要.
- 开发针对GC/PM的有效策略对于改善患者存活率至关重要.
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