相关实验视频

Updated: Jun 3, 2025

The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage

The C-seal: A Biofragmentable Drain Protecting the Stapled Colorectal Anastomosis from Leakage

Published on: November 4, 2010

血清生物标志物的有用性在预测胃切除术后的解剖管泄漏

Diego Ramos^1,2, Enrique Gallego-Colón^2,3, Javier Mínguez⁴

¹General and Gastrointestinal Surgery Department, Hospital Central de la Defensa "Gómez Ulla" CSVE, 28047 Madrid, Spain.

|January 11, 2025

概括

在胃切除术后,C-反应蛋白 (CRP),前素 (PCT) 和中性粒细胞与淋巴细胞的比率 (NLR) 有效地预测了胃切除术后的解静脉泄漏. 这些生物标志物可以帮助排除在术后第一周的泄漏.

科学领域:

胃肠病学胃肠病学
手术瘤学手术瘤学
临床病理学临床病理学

背景情况:

胃切除术 (Gastrectomy) 后的严重并发症之一是静脉漏 (AL).
早期和准确的AL诊断对于患者的治疗结果至关重要.

研究的目的:

评估和比较几种生物标志物的预测准确性,用于胃切除术后早期AL诊断.
评估的生物标志物包括C反应蛋白 (CRP),甲 (PCT),中性粒细胞与淋巴细胞的比率 (NLR),血小板与淋巴细胞的比率 (PLR),纤维素和平均血小板体积 (MPV).

主要方法:

一项前性的双中心观察性研究包括了107名接受选择性胃切除术的患者.
生物标志物的表现被评估为预测AL在前7个术后天 (PODs).

主要成果:

AL发生在20.56%的患者中,诊断通常在POD5.5上.
CRP,PCT,NLR,PLR和纤维素原显示出与AL的显著关联.
与其他早期AL检测生物标志物相比,CRP,PCT和NLR显示出更高的预测准确性.

结论:

CRP,PCT和NLR是排除AL在第一个术后周内有价值的生物标志物.
这些生物标志物为胃切除术后患者的临床决策提供了足够的预测能力.

关键词:

在C-反应性蛋白质中.静体泄漏发生在静体内.生物标志物生物标志物纤维素原体是一种纤维原体.胃切除术是一种胃切除术.血小板的平均体积是多少中性粒细胞与淋巴细胞的比率.血小板与淋巴细胞的比率.这是什么意思? procalcitonin.

更多相关视频

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

相关概念视频

Serum Laboratory Studies, Stool Test, Breath Test

Serum Laboratory Studies, Stool Test, Breath Test

Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...