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Updated: Jun 3, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

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遗传多态性对心力衰竭患者并发症发展的影响

Madina R Zhalbinova1, Saule E Rakhimova1,2, Ulan A Kozhamkulov1,2

  • 1National Laboratory Astana, Nazarbayev University, Astana 010000, Kazakhstan.

Journal of clinical medicine
|January 11, 2025
PubMed
概括

像UGT1A6 rs2070959这样的遗传变异会影响左心室辅助器件 (LVAD) 的心力衰竭患者的阿司匹林有效性. 基因定型可以帮助个性化抗血小板治疗,以预防诸如血栓和出血等并发症.

关键词:
基因型 基因型 基因型心脏衰竭是因为心脏衰竭.左心室辅助装置 (LVAD) 的使用个性化治疗 个性化治疗多形态主义的多态主义.

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