在不同初级诊断的患者中,EQ-5D和HRQ-6D测量的同时有效性
Mohamad Adam Bujang1, Yoon Khee Hon2, Wei Hong Lai1
1Clinical Research Centre, National Institutes of Health, Sarawak General Hospital, Ministry of Health Malaysia, Kuching 93586, Sarawak, Malaysia.
Journal of clinical medicine
|January 11, 2025
概括
新的HRQ-6D有效地衡量与健康相关的生活质量 (HRQOL),显示与已建立的EQ-5D标准的同时有效性. 这支持其在临床研究中用于患者结局的应用.
科学领域:
- 健康 结果 研究 研究 结果
- 心理测量 心理测量 心理测量
- 临床流行病学临床流行病学
背景情况:
- 与健康相关的生活质量 (HRQOL) 对于以患者为中心的护理至关重要.
- EQ-5D是 HRQOL 测量的黄金标准.
- HRQ-6D是开发用于评估HRQOL的新型仪器.
研究的目的:
- 为了评估HRQ-6D与EQ-5D的并发有效性.
- 评估不同初级诊断的不同患者群体的HRQ-6D表现.
主要方法:
- 这是一项涉及149名患有心脏病,癌症,抑郁症或末期脏病 (ESRD) 的患者的横截面研究.
- 使用了两个HRQOL仪器:EQ-5D-3L和HRQ-6D.
- 从2023年1月到5月在三级医院收集的数据.
主要成果:
- 大多数HRQ-6D域与EQ-5D-3L域有显著的相关性 (p < 0.001),控制了初级诊断.
- HRQ-6D的"物理能量"域与EQ-5D-3L的"通常活动"显著相关 (p < 0.001).
- 在整体HRQ-6D得分和EQ-VAS (系数=0.445,p<0.001) 之间发现了显著的相关性.
结论:
- HRQ-6D与EQ-5D具有强大的并发有效性.
- HRQ-6D是衡量患者结果的可靠仪器.
- 临床医生和研究人员可以在干预和观察研究中自信地使用HRQ-6D.
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