在TEM-A单中心实验中治疗的前恶性和早期恶性直肠息肉的局部复发
Muhammad Khalifa1, Rachel Gingold-Belfer2, Nidal Issa1
1Department of Surgery, Rabin Medical Center-Hasharon Hospital, Faculty of Medicine, Tel Aviv University, Petach Tikva 49100, Israel.
Journal of clinical medicine
|January 11, 2025
概括
经过直肠内显微手术 (TEM) 治疗直肠息肉后的复发与较大的瘤大小和粘素产生有关. 个性化后续对这些风险因素的患者至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 结肠直肠手术 结肠直肠手术
背景情况:
- 过内显微手术 (TEM) 是用于直肠多的一个关键的微创手术,包括高度发育不良 (HGD) 和早期直肠癌 (T1).
- 在TEM之后评估复发风险对于优化患者管理和结果至关重要.
研究的目的:
- 评估TEM后高度发育不良 (HGD) 和T1直肠瘤的复发风险.
- 为了确定与TEM治疗后复发相关的重要因素.
主要方法:
- 在2005年至2019年期间,对79名因直肠病变而接受TEM治疗的患者进行了回顾性分析.
- 数据收集包括人口统计,瘤特征 (大小,边缘,粘素生产,距离门边缘的距离) 和随访结果.
- 进行了单独和统一的分析,以确定HGD和T1组的复发预测因素.
主要成果:
- 在统一分析中,较大的瘤大小与复发风险增加显著相关 (OR = 2.27,p = 0.028).
- 在T1组 (p = 0.0012) 和组合分析 (p = 0.014) 中,素的产生强烈预测了复发.
- 从门边缘的距离显示出与复发的边缘关联 (p = 0.053).
结论:
- 较大的瘤大小和粘素生产的存在是用TEM治疗的直肠多瘤中复发的显著预测因素.
- 个性化后续策略和术后管理对于患有已确定的风险因素的患者来说至关重要,以减轻复发的风险.
更多相关视频
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
211
08:26Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
338
相关概念视频
01:21Inflammatory Bowel Disease V: Surgical Management
116
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
116
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
48
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
48
01:25Endoscopic Procedures II: Colonoscopy
56
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
56