探索与饮食和疾病有关的影响,在炎症性肠道疾病中对浮和便气味感知
Lea Pueschel1, Sonja Nothacker2, Leonie Kuhn1
1Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, 30625 Hannover, Germany.
Journal of clinical medicine
|January 11, 2025
概括
炎症性肠道疾病 (IBD) 患者比健康人体体验更多的肠道气味,特别是在活跃的疾病期间. 饮食对肠道健康有影响,但IBD患者和对照人群之间的气味相关性不同.
科学领域:
- 胃肠病学 胃肠病学
- 微生物组研究的研究.
- 饮食科学 饮食科学
背景情况:
- 炎症性肠病 (IBD) 可以改变胃肠功能,可能会影响便和气气味.
- 了解IBD中饮食,肠道微生物组和肠道气味之间的相互作用对于症状管理至关重要.
研究的目的:
- 在炎症性肠病 (IBD) 患者中调查饮食习惯和肠道气味感知之间的关系.
- 为了比较IBD患者和健康对照者 (HCs) 之间的肠道气味流行率和相关因素.
主要方法:
- 一项涉及233名IBD患者和96名健康对照者的横截面研究.
- 评估包括关于饮食习惯 (高度加工食品,遵守地中海饮食),疾病活性 (HBI,PMS,CRP,便calprotectin) 和嗅觉的问卷.
主要成果:
- 与HC相比,IBD患者表现出肠道恶臭的患病率更高.
- 与缓解相比,活跃IBD疾病状态与肠道恶臭增加有关.
- 饮食行为与IBD患者相比,HC患者的恶臭与恶臭的关联较强;男性性别是IBD患者恶臭的风险因素.
结论:
- 饮食因素在控制IBD症状,特别是浮气和便气味方面发挥着重要作用.
- 肠道炎症患者更容易出现肠道恶臭,活跃疾病会加剧这种情况.
- 在IBD患者和健康个体之间存在不同的饮食-肠道健康相互作用模式.
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