在单边腰椎间盘的单边和双边转皮膜外皮注射类固醇注射的比较:随机对照试验
Hanzade Aybüke Ünal1, Ahmet Başarı2, Bahir Kayra Özgencil3
1Department of Anesthesiology and Reanimation, School of Medicine, Ankara University, 06100 Ankara, Turkey.
Journal of clinical medicine
|January 11, 2025
概括
在患有单侧腰椎间盘 (LDH) 的患者中,双边转外皮类固醇注射 (TFESI) 在显著减少50%以上的疼痛方面比单边TFESI更有效. 这两种方法同样减少了整体疼痛和残疾.
科学领域:
- 疼痛管理 疼痛管理
- 神经外科 神经外科
- 放射学 放射学是一门学科.
背景情况:
- 单侧腰椎间盘 (LDH) 往往会导致严重的疼痛和残疾.
- 变形体外皮层类固醇注射 (TFESI) 是LDH的常见治疗方法.
- 单边与双边TFESI对单边LDH的比较疗效尚未得到充分证实.
研究的目的:
- 为了比较单边和双边TFESI在管理单边LDH时的有效性.
- 根据TFESI评估疼痛严重程度,残疾和药物消耗.
主要方法:
- 一项前性,随机,单盲研究,涉及104名单边LDH患者.
- 患者被随机分配,接受单边或双边TFESI.
- 疼痛 (数值评分表-11) 和残疾 (奥斯威斯特残疾指数) 在基线和干预后1周,1个月和3个月被评估.
主要成果:
- 在3个月后,群体之间没有观察到疼痛,残疾或药物使用的统计学上显著差异.
- 双边TFESI在32.6%的患者中降低了超过50%的疼痛评分,而单边TFESI组的这一比例为13.8%.
- 在双边TFESI组中,显著更高比例的患者经历了大量的疼痛缓解.
结论:
- 单边和双边TFESI都有效地减少单边LDH患者的疼痛和残疾.
- 双边TFESI在单级单边LDH患者的疼痛减轻>50%方面表现出卓越的疗效.
- 进一步的研究可能会探索双边TFESI的最佳患者选择.
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