在实施试验中招聘和保留多层次框架:一个说明性的例子
Nathaniel J Williams1,2, Alexandra E Gomes1, Nallely R Vega1
1Institute for the Study of Behavioral Health and Addiction, Boise State University, Boise, ID, USA.
Clinical trials (London, England)
|January 11, 2025
概括
一个新的多层次框架有效地改善了混合试验的招聘和保留,即使是在COVID-19大流行期间. 这种方法增强了在多个参与者层面采用健康干预措施.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 实施科学 实施科学
- 临床试验设计 临床试验设计
背景情况:
- 实施和混合有效性-实施试验加速了有效的健康干预措施的采用.
- 这些试验面临着独特的招聘和保留挑战,原因是多层次的参与者参与和众多的临床场所.
- 为了应对这些挑战,提出了一个新的多层次,基于理论的,以关系为中心的框架.
研究的目的:
- 在实施和混合有效性-实施试验中引入一个新的多层次的招聘和保留框架.
- 在WISP-DOM (Working to Implement and Sustain Digital Outcome Measures) 试验中描述该框架的应用.
- 详细介绍用于克服招聘和保留障碍的战略,包括COVID-19大流行所造成的障碍.
主要方法:
- 根据针对组织领导,临床医生,行政人员和患者的多层次框架制定招聘和保留策略.
- 在整个WISP-DOM试验中应用结构化评估指南来完善方法.
- 为应对COVID-19流行病而调整战略.
主要成果:
- 在WISP-DOM试验中,成功招募了21家诊所,252名临床医生和686名护理人员,达到95%的患者招募目标.
- 尽管存在大流行,但数据完成率很高:领导者/临床医生的数据完成率为90%,护理人员的数据完成率为80%-88%.
- 该研究表明,在多个层面上成功招聘和留住员工.
结论:
- 一个多州混合型III试验在全球大流行期间成功地保持了各个层面的高招聘和保留率.
- 提出的多层次框架,整合行为理论和基于证据的策略,可以适应各种试验类型.
- 这一框架为研究人员进行实施,混合和多层实用试验提供了有价值的工具.
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