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患有严重三腹吐的患者的预后得分:外部验证研究
Consuelo Fernández-Avilés1, Martín Ruiz Ortiz1,2,3,4, Ana Fernández Ruiz1
1Cardiology Department, University Hospital Reina Sofia, Córdoba, Spain.
European journal of clinical investigation
|January 11, 2025
概括
预测严重三回 (TR) 死亡率的四个得分显示出类似的准确性. 这些得分有效地预测了独立患者队列中的死亡和心力衰竭 (HF) 病例.
科学领域:
- 心脏病学 心脏病学
- 临床结果研究研究
- 医疗信息学 医疗信息学
背景情况:
- 在2022年,为三回 (TR) 开发了几种风险分层分数.
- 这些包括TRI-SCORE,Hochstadt分数,Wang分数和TRIO分数.
- 外部验证对于评估它们在现实世界中的适用性至关重要.
研究的目的:
- 为外部验证四个已发表的TR死亡风险得分.
- 为了比较这些分数的辨别能力来预测死亡率和心力衰竭 (HF) 的入院.
- 为了评估重度TR患者的独立队列中的表现.
主要方法:
- 追溯包括了614名患有严重TR的患者.
- 心声学评估和长期随访 (中位数为5年).
- 接收器运行特征 (ROC) 曲线分析,以评估对死亡率和死亡率或HF入院的结合终点的辨别能力.
主要成果:
- 所有四个评分都显示出统计学上显著的辨别能力来预测死亡和结合的终点.
- 对于死亡率预测的C统计数据在0.72到0.75.5之间.
- 综合终点的C统计数据在0.73到0.76.7之间.
- 对于任何终点的分数之间的对对比比较中没有发现显著差异.
结论:
- 所有评估的风险分数都具有显著和可比的歧视力.
- 这些得分在预测严重TR患者的死亡率或HF入院的结合终点方面是有效的.
- 这些发现支持这些评分在临床实践中对风险分层的有用性.
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