相关实验视频
Updated: May 6, 2026

05:53
Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
4.6K
临床特征与狗的宫含水核脉动挤出相关
Megan Lin1, Christopher X Hong2, Mark Rishniw1
1Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Journal of veterinary internal medicine
|January 11, 2025
概括
狗的水合核脉挤出 (HNPE) 与其他宫骨髓病不同,通常影响较老,较轻的狗. HNPE病例更可能需要机械通风,突出了不同的临床需求.
科学领域:
- 兽医神经学 兽医神经学
- 比较病理学比较病理学
背景情况:
- 宫液化核脉冲挤出 (HNPE) 是一种鲜为人知的导致狗宫骨髓病的病因.
- 了解HNPE的临床特征对于将其与其他脊髓疾病区分开来至关重要.
研究的目的:
- 为了比较HNPE与其他宫骨髓病变的狗的临床特征和机械通风需求.
- 确定HNPE案件的陈述和结果的关键差异.
主要方法:
- 追溯研究377个客户拥有的狗 (2010-2022年) 的MRI确认的宫骨髓病.
- 包括的病例:46个HNPE,192个椎间盘挤出 (IVDE),30个纤维软骨栓塞性骨髓病 (FCEM),66个宫脊髓病 (CSM) 和43个瘤.
- 使用双变量分析来比较临床发现和结果.
主要成果:
- 与其他宫髓病相比,患有HNPE的狗年龄较大 (中位数为10岁与8岁),体重较轻 (中位数为9.1公斤与20.2公斤),并且不经常行走 (89%与54%相比).
- 在HNPE病例中,中枢带综合征的发病率较高 (35%对16%) 和非侧面性症状的发病率较高 (65%对48%).
- 与IVDE相比,HNPE狗更有可能需要机械通风 (OR 9.0) 并呈现出较低的疼痛分数.
结论:
- 与其他宫骨髓病相比,狗的HNPE表现出不同的临床特征和表现.
- 在HNPE病例中需要机械通风的可能性更高是临床管理的重要发现.
- 这些差异需要特别考虑诊断和管理犬病患者的HNPE.
更多相关视频
相关概念视频
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
863
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
863
Cushing Syndrome I: Introduction
46
Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the...
46
Cushing Syndrome II: Pathophysiology
56
Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features...
56
Herniated Intervertebral Disc l: Introduction
44
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
44
Degenerative Disc Disease I: Introduction
29
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
29
Degenerative Disc Disease ll: Pathophysiology
34
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
34

