建议并探索一种新的评分来量化患者感知到的常规护理下炎症性肠病负担
Joseph L Pipicella1,2,3, Bonita Gu2,4, Jack McNamara3,4
1Crohn's Colitis Cure, Sydney, New South Wales, Australia.
大多数炎症性肠病患者报告轻度或没有患者感知的疾病负担 (PPBoD). 较高的PPBoD可能会通过先进疗法得到改善,这表明需要在管理IBD时进行治疗升级.
科学领域:
- 胃肠病学 胃肠病学
- 临床医学 临床医学
- 患者报告的结果
背景情况:
- 炎症性肠病 (IBD) 的负担通常从系统或经济的角度来看.
- 开发了一种新的患者感知疾病负担 (PPBoD) 评分,并在澳大利亚大队列中进行评估.
- 这项研究将重点转移到患者对IBD的实践经验.
研究的目的:
- 开发和验证一种新的PPBoD评分,用于性结肠炎 (UC),克罗恩氏病 (CD) 和IBD未分类 (IBDU).
- 在澳大利亚IBD队列中,将PPBoD得分与人口,疾病和治疗因素相关联.
- 了解患者对疾病影响的观点,超越传统的临床指标.
主要方法:
- 利用克罗恩结肠炎护理注册表 (2023年10月) 的数据,包括IBD和最近门诊护理的成年人.
- 在UC,CD和IBDU患者群体中开发并应用了新的PPBoD得分.
- 与患者人口统计,疾病特征和治疗方式相关联的PPBoD得分.
主要成果:
- 很大一部分患者报告没有 (46.7%) 或轻度 (34.6%) PPBoD.
- 与性结肠炎 (UC) 相比,更高的PPBoD与克罗恩病 (CD) 和IBD未分类 (IBDU) 相关,并且在女性中更为普遍.
- 没有或轻度PPBoD的患者更有可能接受先进疗法,而较高的类固醇使用与较高的PPBoD相关.
结论:
- 这个现实世界队列中的大多数患者经历了患者感知疾病负担 (PPBoD) 的最小程度.
- 研究结果表明,升级疗法可以有效地管理更高水平的PPBoD.
- 这凸显了患者报告结果在指导IBD管理中的重要性.
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