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在接受ICU治疗的患者中,压力诱导的高血糖率与败血症风险之间的关联
Yanjun Xu1, Jing Yang1, Zexing Jiang1
1Department of Critical Care Medicine, Xuzhou Renci Hospital, China.
压力诱导高血糖比率 (SHR) 的升高与ICU患者的败血症风险增加有关. 监测SHR可能有助于识别高风险个体,以便及时介入.
科学领域:
- 临界护理医学 临界护理医学
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
背景情况:
- 败血症是一种危及生命的免疫反应对感染.
- 压力高血糖症在危急疾病中很常见,并且与不良结果有关.
- 压力诱导高血糖比率 (SHR) 和败血症风险之间的关联尚不清楚.
研究的目的:
- 调查重症监护室 (ICU) 患者中SHR和败血症发展之间的相关性.
- 为了确定SHR是否可以作为败血症的预测标记.
主要方法:
- 使用MIMIC-IV数据库进行回顾性队列研究.
- 包括ICU患者在入院24小时内血糖和HbA1c水平.
- 使用后勤回归来分析SHR和败血症风险之间的关联,调整混因素.
主要成果:
- 较高的SHR水平与败血症风险增加显著相关 (OR = 1.53).
- 这种关联在子组中是一致的:老年患者 (≥65岁),男性和没有2型糖尿病的患者.
- 基线血糖水平与败血症风险没有显著关联.
结论:
- 升高的SHR与ICU患者的败血症风险更高相关.
- SHR监测可以成为早期毒风险识别的宝贵工具.
- 临床干预可以通过床边的SHR监测来促进.
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