改善脂肪球体结构,缩小母乳和婴儿配方奶粉之间的代谢物差距
Yue Sun1, Xueying Zhang2, Jiayu Li2
1Food College, Northeast Agricultural University, No.600 Changjiang St., Xiangfang Dist, 150030 Harbin, China; School of Food Science and Engineering, Hainan University, No. 58 People Avenue, Meilan Dist, 570228, Haikou, China.
Food chemistry
|January 11, 2025
概括
具有乳脂球体膜 (MFGM) 结构的婴儿配方奶粉密切模仿母乳的代谢特性. 这项研究强调了MFGM在婴儿营养中的作用,改善了婴儿配方成分,以改善婴儿发育.
科学领域:
- 营养生物化学 营养生物化学
- 食品科学 食品科学 食品科学
- 代谢学 代谢学 代谢学
背景情况:
- 人母乳成分是婴儿营养的黄金标准.
- 婴儿配方奶粉旨在复制母乳的好处,包括代谢性质.
- 乳脂球膜 (MFGM) 在人乳的结构和功能中起着至关重要的作用.
研究的目的:
- 调查使用MFGM修改婴儿配方脂肪球体结构是否可以改善与母乳的代谢相似性.
- 为了比较不同婴儿配方原型与母乳的代谢概况.
主要方法:
- 制备两个模型婴儿配方奶粉 (F1:MFGM涂层脂肪球;F2:蛋白质涂层脂肪球) 并使用商业MFGM婴儿配方奶粉.
- 代谢分析以比较婴儿配方奶粉与母乳的代谢概况.
- 识别差异性代谢物和对代谢途径的丰富分析.
主要成果:
- 与母乳相比,F1配方显示了60种不同的代谢物,远远少于F2 (132) 和商业配方 (126).
- 鉴定出甘油胆是潜在的生物标志物,可以将婴儿配方与母乳区分开来.
- 氨基酸和脂质代谢途径显示F1和母乳之间的丰富差异较小,与F2和商业配方相比.
结论:
- 使用MFGM增强的脂肪球体的婴儿配方奶粉 (F1) 显示出与人乳具有最高的代谢相似性.
- 在脂肪球体中MFGM的结构性作用是婴儿配方奶粉中实现类似人乳的代谢特性的关键.
- 在婴儿配方中优化MFGM结构可以改善婴儿的新陈代谢调节.
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