间歇性禁食和神经认知障碍:证据显示的是什么
Jordan Beveridge1, Allison Montgomery1, George Grossberg1
1St. Louis University Department of Psychiatry and Behavioral Neuroscience, Monteleone Hall, 1438 South Grand Boulevard, St. Louis, MO 63104, United States.
The journal of nutrition, health & aging
|January 11, 2025
概括
间歇性禁食通过增强大脑健康,显示出对认知衰退的治疗潜力. 需要进一步的研究来证实其在人类中的长期安全性和有效性.
科学领域:
- 神经科学是一个神经科学.
- 代谢健康 代谢健康
- 老年学是一门学科.
背景情况:
- 间歇性禁食 (IF) 是作为治疗认知障碍的治疗策略.
- 专注于IF对神经可塑性,炎症和认知功能的影响.
研究的目的:
- 审查IF在认知衰退中的治疗潜力.
- 评估对神经可塑性,炎症和认知功能的影响.
主要方法:
- 进行了PubMed文献的叙事审查.
- 包括过去十年关于FI和神经认知/神经可塑性的人类和动物研究.
主要成果:
- 临床前数据显示,IF可以促进神经发生和突触可塑性.
- 在认知障碍的动物模型中,IF可以减少神经炎症.
- 有限的人类研究表明,IF可以改善认知和减少氧化应激.
结论:
- 对于认知障碍患者来说,IF显示出治疗的前景.
- 强有力的临床前证据支持神经保护机制.
- 需要更多标准化的人体研究来证实有效性和安全性.
关键词:
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