响应抑制中的右下额叶皮和前SMA:基于PTC模型的调查
Lili Wu1, Mengjie Jiang1, Min Zhao2
1Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, China.
NeuroImage
|January 11, 2025
概括
这项研究阐明了响应抑制,通过显示右下额叶皮层 (rIFC) 暂停了运动反应,而补充前运动区域 (preSMA) 则阻止了它们,支持暂停然后取消模型.
科学领域:
- 认知神经科学 认知神经科学
- 神经成像是一种神经成像.
- 发动机控制器的控制器
背景情况:
- 反应抑制对于认知功能至关重要.
- 补充前运动区域 (preSMA) 和右下额叶皮层 (rIFC) 是抑制控制网络的关键.
- 它们在响应抑制中的具体作用仍在争论中.
研究的目的:
- 用暂停-然后-取消模型研究preSMA和rIFC在响应抑制中的功能特异性.
- 在停止过程中区分preSMA和rIFC的角色.
- 利用fMRI检查抑制控制的神经机制.
主要方法:
- 使用了功能磁共振成像 (fMRI).
- 参与者完成了去/不去任务 (GNGT) 和停止信号任务 (SST).
- 使用GNGT来分离暂停过程;这两项任务都研究了抑制机制.
主要成果:
- 在响应抑制过程中,GNGT和SST都激活了preSMA和rIFC.
- 增加的rIFC激活与GNGT中延迟的启动反应相关.
- 在这两项任务中,增加的前SMA激活与通过条纹体增强的抑制效率相关.
结论:
- 结果支持暂停然后取消模型.
- rIFC参与了暂停过程,延迟了运动反应.
- 前SMA参与停止运动反应,特别是通过条状通路.
关键词:
一个暂停然后取消 (PTC) 模型.功能性磁共振成像 (fMRI) 是一种功能性磁共振成像.预补充电机区 (preSMA) 预补充电机区响应抑制反应的抑制.右下额叶皮层 (rIFC) 是指右下额叶皮层.更多相关视频
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