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Updated: Jun 3, 2025

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孕产妇的肥胖会改变由EZH2和AMPK之间的相互作用介导的基因组修饰,从而损害发育中的胚胎大脑皮层中的神经分化

Thilina T Alawathugoda1, Muhammad Abid Sheikh1, Anil Kumar Challagandla2

  • 1Department of Biochemistry, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, Abu Dhabi, United Arab Emirates.

The Journal of biological chemistry
|January 11, 2025
PubMed
概括

孕产妇的肥胖会破坏胚胎大脑的发育,通过基因调节改变基因调节通过基因组修饰的表观遗传变化,影响神经发生,并可能导致神经发育障碍.

关键词:
在 ChIP-seqq.在RNA-seqqq.胚胎神经发生.表观遗传学是指表观遗传学.孕产妇的肥胖症 孕产妇的肥胖症

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