沈注射加益生菌改善了部分胃切除术后胃癌患者的营养状况
1Department of General Surgery, Yulin First Hospital, Yulin, Shaanxi, China.
Pakistan journal of pharmaceutical sciences
|January 12, 2025
概括
益生菌通过增强免疫功能和营养状况,显著改善胃癌 (GC) 患者的术后恢复. 与Shenqi注射的联合治疗进一步提高了关键的免疫标记物,改善了预后.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
背景情况:
- 胃癌 (GC) 发病率正在上升,手术往往导致术后结果不佳.
- 众所周知,益生菌可以增强胃肠功能和免疫力.
- 需要有效的策略来改善GC患者的术后恢复和预后.
研究的目的:
- 评估益生菌在改善GC患者术后康复方面的疗效.
- 为了比较单独使用益生菌与联合治疗 (益生菌+沈奇注射) 对患者结局的影响.
主要方法:
- 一项随机研究涉及135名经过彻底切除的GC患者.
- 研究对比了三个组:对照组 (常规治疗),益生菌组 (常规+益生菌),组合组 (常规+益生菌+Shenqi注射).
- 评估了手术后的结果,免疫功能 (CD4 +,CD8 +) 和营养状况 (ALB,HGB,PA,TP).
主要成果:
- 与传统方法相比,益生菌显著缩短了术后康复期.
- 益生菌改善了GC患者的免疫功能和营养状况.
- 组合组显示CD4 +,ALB,HGB,PA和TP的水平较高,CD4 +/CD8 +比益生菌组的比例更低.
结论:
- 益生菌在加速术后恢复和提高GC患者的免疫和营养状况方面是有效的.
- 与Shenqi注射的联合治疗可能在改善特定的免疫标志物和预后方面提供额外的好处.
- 对组合疗法的进一步研究可以优化GC手术后的患者结果.
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