在睡眠内镜中确定最佳镇静深度,使用双光谱学和同时进行多睡眠学
Öznur Gündüz1, Kürşat Murat Özcan2, Fatma Cemre Sazak Kundi3
1Department of Otorhinolaryngology, Ankara Bilkent City Hospital, Ankara, Turkey. oznrgundz@gmail.com.
概括
在药物诱导睡眠内镜 (DISE) 期间进行更深的镇静会增加中央呼吸暂停和脱. 60-75的最佳BIS范围是最好的评估阻塞性呼吸暂停和阻塞性睡眠暂停患者的打.
科学领域:
- 睡眠医学 睡眠医学
- 麻醉学 麻醉学
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种常见的疾病,在睡眠期间重复出现上呼吸道崩.
- 药物诱导睡眠内镜 (DISE) 是评估OSA呼吸道阻塞的位置和程度的宝贵工具.
- 确定DISE的最佳镇静深度对于准确评估呼吸系统事件至关重要.
研究的目的:
- 评估在OSA患者的DISE期间振动和阻塞的局部化和配置.
- 为了确定DISE的最佳镇静深度,以准确评估气道动态.
- 为了将双光谱指数 (BIS) 值与呼吸事件和阻塞模式相关联.
主要方法:
- 对42名OSA患者进行前性研究,这些患者同时接受了多睡眠图和DISE.
- 用静脉注射药物实现镇静,使用BIS进行监测.
- 使用芬太尼,米达佐拉姆和普罗波输液进行的DISE;数据统计分析.
主要成果:
- 降低的BIS值与增加的呼吸力减少和脱度相关.
- 在BIS 65以下观察到的中央呼吸暂停,随着深度镇静而增加.
- 阻塞性呼吸暂停在BIS 70以上占主导地位,而最常见的是后面的阻塞.
- 振动发生在90%以上的患者中,BIS范围为60-70.
结论:
- 增加DISE镇静深度与更高的中央呼吸暂停和脱度的频率有关.
- 在DISE期间评估阻塞性呼吸暂停和打的最佳镇静深度在BIS范围内的60-75.
- 这种BIS范围有助于在OSA患者中准确评估上呼吸道阻塞和振动.
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