身体成分指数与血管健康之间的关联:系统性审查和元分析
Mohammad Nikoohemmat1, Amirhossein Ramezani Ahmadi2, Ali Valizadeh1,3
1Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Eating and weight disorders : EWD
|January 12, 2025
概括
这一元分析表明,身体脂肪百分比与动脉硬有关,而无脂肪质量与动脉结构有关. 需要进一步研究特定的身体组成指标和血管健康影响.
科学领域:
- 心血管健康 心血管健康
- 身体组成分析 身体成分分析
- 血管生物学 血管生物学
背景情况:
- 身体成分显著影响生理功能,包括心血管健康.
- 骨肌肉量和脂肪量是代谢和心血管风险的关键决定因素.
- 动脉硬度和结构是血管健康的关键指标,并预测心血管事件.
研究的目的:
- 系统地审查和元分析身体组成参数和血管健康指数之间的关系.
- 调查骨肌肉质量,脂肪质量,以及动脉硬度 (PWV,CAVI) 和结构 (cIMT) 的测量之间的关联.
主要方法:
- 在主要数据库中进行了全面的文献搜索,直到2024年1月.
- 包括观察性研究 (横截面,纵向) 评估身体组成和血管健康.
- 随机效应元分析和灵敏度分析对15项研究的数据进行 (n=21,215).
主要成果:
- 在无脂肪质量 (FFM) 和动脉内膜介质厚度 (cIMT) 之间发现了积极的关联.
- 身体脂肪百分比 (BFP) 与脉冲波速度 (PWV) 有积极的关联.
- 此外,FFM与心血管指数 (CAVI) 有积极关联,但尾骨肌 (ASM) 与cIMT没有显著联系.
结论:
- 身体组成,特别是FFM和BFP,与血管健康标志物有显著的关联.
- 这些发现强调了身体组成和心血管结构/功能之间的复杂相互作用.
- 需要进一步的研究来探索特定的身体成分指数及其对血管健康的临床相关性.
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