miR-449a/miR-340 重新编程细胞身份和新陈代谢在融合阴性狂宫肌肉瘤

Enrico Pozzo1, Laura Yedigaryan1, Nefele Giarratana1

  • 1Translational Cardiomyology Laboratory, Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.

Cell reports
|January 12, 2025
PubMed
概括

微RNA miR-449a 和 miR-340 通过向线粒体的酸盐载体 (MPC) 来调节聚变阴性拉布多米索尔科马 (FN-RMS) 细胞身份. 抑制MPC将FN-RMS细胞转移到非瘤状态.

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