在健康男性急性睡眠剥夺下,杏仁体形态和认知功能的调制模式在急性睡眠剥夺下
Haoyuan Zhang1, Lili Xu2, Xiaohan Yi1
1School of Psychology, Northwest Normal University, Lanzhou, Gansu, China.
Sleep medicine
|January 12, 2025
概括
急性睡眠不足 (ASD) 会损害空间工作记忆 (SWM) 并改变杏仁核子区域的体积. 杏仁体中的杏仁体.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 睡眠研究 睡眠研究
背景情况:
- 杏仁体对于行为和精神疾病至关重要,睡眠障碍会影响其结构.
- 虽然已知慢性睡眠剥夺的影响,但急性睡眠剥夺对杏仁体形态和认知的影响还未得到充分研究.
研究的目的:
- 调查急性睡眠不足 (ASD) 如何调节杏仁体子区域体积和空间工作记忆 (SWM) 性能.
- 为了探索杏仁体形态变化和24小时睡眠丧失后SWM任务表现之间的关系.
主要方法:
- 28名健康的男性在ASD24小时前后接受了MRI扫描和SWM任务.
- 杏仁体子区域被细分,格兰杰因果分析检查了形态学-认知关系.
- 测量SWM准确度和反应时间以评估认知表现.
主要成果:
- ASD导致SWM精度降低和反应时间增加.
- 杏仁体子区域的显著体积变化:左皮层-杏仁体过渡区域 (CAT) 的增加和右侧侧核 (PL) 的减少.
- 格兰杰因果关系揭示了中心介质和皮质类核之间的双向调制,随着难度的增加,桃体在SWM中逐渐参与.
结论:
- 急性睡眠不足显著影响杏仁体形态和空间工作记忆.
- 杏仁体在睡眠不足下调节认知表现方面发挥着至关重要的作用.
- 不同桃体子区域的参与表明,一个适应性系统试图在睡眠丧失期间保持认知功能.
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