周围神经纤维光链和皮质内髓在双相I型情绪障碍中

Mohammad Ali1, Bianca Wollenhaupt-Aguiar2, Manpreet Sehmbi3

  • 1MiNDS Neuroscience Graduate Program, McMaster University, Hamilton, ON, Canada; Centre for Clinical Neurosciences, McMaster University, Canada.

PubMed
概括

患有双相情感障碍 (BD) 的个人表现出血清神经丝光链 (NfL) 水平升高,这是大脑形态缺陷的潜在指标. 这项研究将较高的NfL与BD患者在特定大脑区域的皮层内髓 (ICM) 变化联系起来.

相关概念视频

Bipolar Disorder01:30

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
50
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
120
Types of Intermediate Filaments01:31

Types of Intermediate Filaments

The intermediate filaments are an essential component of the cytoskeleton. Presently six types of intermediate filament have been identified. Type I and II are acidic and basic keratin proteins. Type III is of mesodermal origin and comprises four proteins: vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Vimentin is commonly found in mesenchymal cells, desmin in muscle cells, GFAP in astrocytes, while peripherin is found in peripheral nervous system neurons (PNS). Type...
3.6K