伴心经管边缘到边缘修复对左心室体积和功能的超急性影响
Mohammad Kassar1, Ana Ovsenik2, Raouf Madhkour2
1Department of Cardiology, Inselspital, Bern University Hospital; Graduate School for Health Sciences, University of Bern, Switzerland; Clinic for General and Interventional Cardiology/Angiology, Heart- and Diabetes Center, Bad Oeynhausen, Germany.
The American journal of cardiology
|January 12, 2025
概括
过导管边缘到边缘修复 (TEER) 严重降低左心室 (LV) 功能,特别是喷射分数和应变,与额头回减少相关. 相对的LV射出分数减少预测了TEER后的死亡率.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 干预心脏病学 干预心脏病学
背景情况:
- 在高风险患者中,严重的有症状的腹 (MR) 往往需要干预.
- 过导管边缘到边缘修复 (TEER) 是严重的MR治疗的一种既定治疗方法.
- TEER对左心室 (LV) 功能的急性影响需要使用高级心声回声学进行进一步的研究.
研究的目的:
- 调查TEER对LV体积和功能的直接影响.
- 评估这些急性变化对中期结果的影响.
- 使用高分辨率的3维透食管心声谱进行详细的LV评估.
主要方法:
- 研究了80名接受TEER治疗严重MR的患者.
- 使用了高分辨率的3维透食管心声学.
- 在TEER之前和之后分析了LV体积,射出分数和全球纵向/周围应变.
主要成果:
- TEER导致 LV 末端透缩体积和中风体积显著减少,而末端缩体积增加.
- 左心室喷射分数 (LVEF),全球纵向应变和全球周围应变在TEER后明显恶化.
- 相对的LVEF降低被确定为死亡率最强的预测因素 (HR1.76每10%降低).
结论:
- 在TEER后的急性LV功能下降与MR减少的程度有关.
- 周围功能和基线LVEF较高的患者经历了更大的影响.
- 相对减少LVEF是预测TEER后死亡率的关键心声标记.
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