lumbosacral epidural脊柱注射和 lumbosacral epidural脂质瘤之间是否存在一种关系? 一个回顾性研究研究
Ali A Al-Omari1, Naser Obeidat2, Adham F Alnemer1
1Department of Special Surgery, Division of Orthopedic Surgery, King Abdullah University Hospital, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan.
Neuro-Chirurgie
|January 12, 2025
概括
腹腔膜外周类固醇注射 (LESI) 可能与腹腔膜外周脂质病 (LEL) 的发展或恶化有关. 需要进一步的研究来证实LESI和LEL之间的这种联系.
科学领域:
- 放射学 放射学是一门学科.
- 疼痛管理 疼痛管理
- 内分泌学 在内分泌学.
背景情况:
- 腹腔膜外周脂质病 (Lumbosacral epidural lipomatosis,简称LEL) 是一种病症,其特征在于外周腔内有多余的脂肪.
- 脊柱外皮类固醇注射 (LESI) 与LEL的发病或进展之间的潜在关联,特别是在没有典型风险因素的患者中,需要进行调查.
研究的目的:
- 探索LESI与LEL的发展或进展之间的关系.
- 为了确定与LEL相关的潜在风险因素或趋势,以下是LESI.
主要方法:
- 一个回顾性,单中心研究包括268名接受LESI的患者.
- 收集的数据包括患者人口统计学,皮质类固醇类型 (主要是甲基普雷迪尼索隆),注射次数,指导方式 (主要是光镜) 和通过MRI对LEL进行分级.
- 排除标准包括缺乏干预前和后的MRI,以及糖尿病或内分泌病症等先前存在的疾病.
主要成果:
- 在268名患者中,7.5%的患者在LESI后LEL等级发生变化.
- 一个趋势表明男性性别和LEL发生之间存在联系.
- 甲基普雷迪尼索隆是最常用的皮质类固醇,大多数患者只接受了一次LESI.
结论:
- 该研究表明,LESI与LEL的发展或进展之间存在潜在的关联.
- 建议进行更大规模的受控成像研究,以进一步调查这种关系.
相关概念视频
01:29Local Anesthetics: Clinical Application as Epidural Anesthesia
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Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
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01:11Local Anesthetics: Clinical Application as Spinal Anesthesia
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Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
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