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Updated: Jun 3, 2025

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
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An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

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MAF1通过促进免疫刺激性瘤微环境来抑制肝癌发生

Di Cao1,2, Yue-Ning Wang1, Chao-Yue Sun3

  • 1State Key Laboratory of Oncology in South China, and Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.

Journal for immunotherapy of cancer
|January 12, 2025
PubMed
概括

MAF1通过激活PTEN并增强抗瘤免疫力,在肝细胞癌 (HCC) 中充当瘤抑制剂. 这一发现表明MAF1可以改善HCC免疫疗法,特别是在缺乏T细胞的患者中.

关键词:
免疫检查点抑制剂 免疫检查点抑制剂瘤微环境 - - 瘤微环境

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