(多) 摄入量,体重和体力活动变化与炎症概况的预期关联
María Rubín-García1, Facundo Vitelli-Storelli2, Laura Álvarez-Álvarez2
1Group of Investigation in Interactions Gene-Environment and Health (GIIGAS), Institute of Biomedicine (IBIOMED), Universidad de León, León, Spain; CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Nutrition, metabolism, and cardiovascular diseases : NMCD
|January 12, 2025
概括
增加饮食中的多醇摄入量和体育活动与减少炎症有关,减轻体重在这种有益影响中起着关键的调解作用.
科学领域:
- 营养免疫学 营养免疫学
- 代谢健康 代谢健康
- 炎症研究 炎症研究
背景情况:
- 慢性炎症是代谢疾病的一个关键因素.
- 饮食中的 (多) 和体育活动 (PA) 是已知的炎症调节剂.
- 了解饮食,生活方式和炎症之间的相互作用对公共健康至关重要.
研究的目的:
- 预期评估 (多) 摄入量,体重 (BW) 和体力活动 (PA) 变化与一年内炎症评分变化之间的关联.
- 为了研究体重变化在 (多) 摄入量和炎症之间的关系中的调解作用.
主要方法:
- 从PREDIMED-Plus研究中对484名参与者的前性观察分析.
- 通过经过验证的食物频率问卷和Phenol-Explorer数据库来评估 (多) 的摄入量.
- 炎症评分从8个血液生物标志物计算;使用结构方程和调解分析分析的关联.
主要成果:
- 较高的 (多) 摄入量与炎症评分和BW的降低相关.
- 增加的PA与较低的炎症评分和BW相关.
- 体重量下降与炎症评分的降低显著相关,介导了 (多) 摄入对炎症影响的22%.
结论:
- 在增加 (多) 摄入量和炎症状态之间存在反向关联.
- 体重减轻显著调解了 (多) 摄入的抗炎作用.
- 促进 (多) 的消费和体重管理策略可以减少炎症.
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