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使用单细胞RNA测序对 NK 细胞进行表征,用于患有急性-慢性肝衰竭的患者

Ninghui Zhao1,2, Han Wang2, Miaoxin Zhang1

  • 1Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Journal of gastroenterology and hepatology
|January 12, 2025
PubMed
概括

单细胞RNA测序确定了急性-慢性肝衰竭 (ACLF) 中明显的自然杀手 (NK) 细胞子集. 炎症NK细胞与ACLF进展和不良结果有关,CEMIP2作为潜在的疾病标志物.

关键词:
急性-慢性性肝衰竭之间存在差异.诱导细胞迁移的氨基酶2 (CEMIP2)这是一种炎症炎症炎症炎症.自然杀手细胞是自然杀手细胞.一个单细胞RNA测序.

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Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...