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Updated: Jun 3, 2025

In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice
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一种小分子药物用于自我检查线粒

Yanan Gao1, Qingjie Bai1, Youxiao Ren1

  • 1State Key Laboratory of Advanced Drug Delivery and Release Systems, School of Pharmaceutical Sciences, Neck-Shoulder and Lumbocrural Pain Hospital, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, 250117, PR China.

Angewandte Chemie (International ed. in English)
|January 12, 2025
PubMed
概括

这项研究引入了一种新型的线粒体吞自我检查药物 (MitoSC),该药物同时破坏线粒体膜潜能,并报告了这一过程. 这种双重作用药物可以实时监测线粒,克服外部标志物的局限性.

关键词:
双重本地化是可以实现的.Lysosomes 是一个溶解体.线粒体中的线粒体.自我检查药物的药物.亚细胞动态 亚细胞动态

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