邻居环境与认知功能和结构性大脑措施的关联在老年非洲裔美国人中
Dima L Chaar1, Le Tu2, Kari Moore3
1Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
BMC medicine
|January 12, 2025
概括
邻里食品环境,就像快餐店一样,与老年非洲裔美国人的更好的认知功能有关. 但DNA甲基化并没有调解这种关系,这表明其他途径也会影响大脑健康.
科学领域:
- 环境健康 环境健康
- 神经科学是一个神经科学.
- 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
背景情况:
- 邻里环境会影响老年人的认知功能和痴呆风险.
- 这些因素包括社会经济地位,食物获取和社会参与.
- DNA甲基化可能会调解这些邻居认知联系.
研究的目的:
- 调查DNA甲基化是否调解了邻居特征与认知功能或白质过强度 (WMH) 之间的关联.
- 研究的重点是年长的非裔美国人没有痴呆症的参与者.
主要方法:
- 检查了外围血液白细胞中的DNA甲基化.
- 在住宅周围使用1英里缓冲区评估邻里特征.
- 在基因流行病学动脉病症网络 (GENOA) 参与者中分析了认知功能 (N=542) 和WMH (N=466).
主要成果:
- 每平方英里增加的快餐和酒精销售商店名义上与改善的视觉概念追踪和延迟的回忆有关.
- 在邻里特征和WMH之间没有发现任何关联.
- DNA甲基化并没有调解观察到的邻居认知关联.
结论:
- 某些邻居的食物环境可能与认知措施有关,可能是通过社交互动.
- 复制是必要的,以确认这些发现.
- 对邻居认知路径的进一步研究可以为健康的大脑衰老提供信息.
关键词:
酒精饮料 酒精饮料 酒精饮料 酒精饮料建筑环境 建筑环境认知功能 认知功能认知健康 认知健康快餐是一种快餐.食品 环境 食品 环境健康的衰老 健康的衰老邻里环境 邻里环境社会环境 社会环境白质的超强度是白质的超强度.更多相关视频
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