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Updated: Apr 11, 2026

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通过计算机辅助药物设计开发新型Lin28抑制剂

Victor M Matias-Barrios1, Mariia Radaeva1, Graciella Rosellinny1

  • 1The Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, 2660 Oak Street, Vancouver, BC, V6H 3Z6, Canada.

Cell death discovery
|January 12, 2025
PubMed
概括

研究人员发现了Ln268,一种针对Lin28 (癌症干细胞的关键调节剂) 的新型化合物,用于对抗耐治疗瘤. 这种候选药物抑制了Lin28的活性,对癌症治疗开发有前途.

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