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Updated: Jun 3, 2025

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功能性静止状态连接与IL-6和TNF-α在抑郁症和健康对照中的差异性相关

Christian N Schmitz1,2,3, Gebhard Sammer4,5,6, Elena Neumann7

  • 1Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, J5, 68159, Mannheim, Germany.

Scientific reports
|January 12, 2025
PubMed
概括

像IL-6和TNF-α这样的外围炎症标志物与抑郁症中的大脑网络连接有关. 这项研究揭示了抑郁症患者与健康对照者的炎症和静止状态网络之间的明显关联.

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相关概念视频

T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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