从2004年到2024年对葡萄糖分解和前列腺癌研究的图书统计分析
Congxu Zhu1, Jingjing Yang1, Lumei Liu1
1School of Integrated Chinese and Western Medicine, Hunan University of Chinese Medicine, No. 300 Bachelor's Road, Changsha, 410208, China.
Discover oncology
|January 12, 2025
概括
这种文献计量分析揭示了越来越多的研究重点是前列腺癌 (PCa) 中增强的糖解. 关键领域包括纳米技术,lncRNAs和miRNAs,提供新的诊断和治疗途径.
科学领域:
- 在瘤学瘤学.
- 代谢研究研究 代谢研究
- 图书统计学 图书统计学
背景情况:
- 前列腺癌 (PCa) 是全球流行的一种恶性瘤.
- 增强的糖解和乳酸分泌是癌症进展的关键驱动因素.
- 了解PCa糖解的研究趋势对于推进治疗至关重要.
研究的目的:
- 从2004年到2024年,系统地分析前列腺癌 (PCa) 中糖解的研究趋势.
- 确定PCa糖解研究中的关键研究热点,有影响力的出版物和新兴前沿.
- 为该领域提供全面的文献统计概述.
主要方法:
- 在Web of Science和PubMed数据库的系统文献搜索 (2004-2024年).
- 使用CiteSpace软件对国家,机构,期刊和关键字可视化进行图书统计分析.
- 用于期刊协作网络映射的VOSviewer软件.
主要成果:
- 共发表了408篇文章,显示了研究成果的上升趋势.
- 美国在出版量和研究中心性方面处于领先地位.
- "癌症研究"和"前列腺癌症"被确定为关键期刊.
- 确定了四个主要研究方向:糖解在PCa中的作用,诊断/预后中的临床价值,抑制剂/天然产品的治疗潜力和耐药性机制.
- 新兴的研究重点是纳米技术,长非编码RNAs (lncRNAs) 和微RNAs (miRNAs).
结论:
- 图书统计分析提供了对两十年来PCa糖解研究的全面概述.
- 确定了关键的研究热点和新兴领域,包括纳米技术,lncRNA和miRNA.
- 这些新兴领域正在推动PCa糖解的创新研究方向.
关键词:
图书统计学分析在CiteSpace中使用CiteSpace.葡萄糖溶解是什么? 葡萄糖溶解热点地区是热点地区.前列腺癌是什么意思 前列腺癌是什么意思趋势 趋势 趋势在VOSviewer中使用VOSviewer.更多相关视频
相关概念视频
02:49Cancer Therapies
7.5K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.5K
03:03mTOR Signaling and Cancer Progression
3.7K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
The mTOR pathway or the...
3.7K
01:22PI3K/mTOR/AKT Signaling Pathway
3.4K
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that regulates growth, proliferation, and cell survival in response to hormones, growth factors, or nutrient availability. This kinase exists in two structurally and functionally distinct forms: mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2). The first form (mTORC1) is composed of a rapamycin-sensitive Raptor and proline-rich Akt substrate, PRAS40. In contrast, mTORC2 consists of a...
3.4K
01:25Protein Glycosylation
6.8K
Glycosylation, the most common post-translational modification for proteins, serves diverse functions. Adding sugars to proteins makes the proteins more resistant to proteolytic digestion. Glycosylated proteins can act as markers and receptors to promote cell-cell adhesion. Additionally, they have many essential quality control functions in the cell, such as correct protein folding and facilitating transport of misfolded proteins to the cytosol, which can be degraded.
Glycosylation occurs in...
Glycosylation occurs in...
6.8K
02:07Tumor Progression
6.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.2K
01:21Cancer Survival Analysis
328
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
328