在精神疾病中注意力缺陷过度活动障碍的流行:系统性审查和元分析
Nicholas Cheng1,2,3, Shayden Bryce2,3,4, Michael Takagi1,5
1Turner Institute for Brain and Mental Health, Monash University, Clayton, Victoria 3168, Australia.
注意缺陷多动症 (ADHD) 影响了18.49%的精神病患者,这一比例高于一般人群. 患病率因诊断标准,发病年龄,地区和出版年份而异.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 神经发育障碍 神经发育障碍
- 精神病性疾病 精神病性疾病
背景情况:
- 注意缺陷多动障碍 (ADHD) 经常在患有精神病的人群中观察到.
- 在精神疾病中报告的ADHD患病率表现出显著的变化.
- 导致这种变化的因素尚不清楚.
研究的目的:
- 系统地审查和元分析ADHD在精神疾病中的患病率.
- 为了确定与报告的ADHD患病率的广泛变化相关的因素.
主要方法:
- 在2023年5月进行了主要生物医学数据库 (MEDLINE,Embase,PsycINFO,CINAHL,Scopus) 的全面搜索.
- 包括报告精神疾病样本中ADHD频率的研究.
- 进行了聚合流行率元分析,子组分析和元回归,以探索影响因素.
主要成果:
- 分析了包括30726个人的36项研究.
- 在精神疾病中,ADHD的综合终身患病率为18.49% (95% CI 11.78%-27.83%).
- 更高的患病率与DSM-IV标准,儿童发病精神病,北美样本和早期出版年份有关.
结论:
- 在精神疾病中,多动症比在普通人群中更为普遍,因此需要临床关注.
- 患病率的显著异质性受诊断标准,精神病发病年龄,地理区域和研究设计的影响.
- 未来的研究应该采用严格的ADHD评估协议来澄清这些因素.
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