细分分体切除术与性结肠炎的总分体切除术:一个系统的审查和元分析
Eddy P Lincango1, Oscar Hernandez Dominguez1, Tara M Connelly1
1Cleveland Clinic, Cleveland, Ohio, USA.
分段性结肠切除术 (SEG) 和全方位结肠切除术 (TPC) 在性结肠炎 (UC) 患者的术后结果相似. 然而,低质量的证据阻止了对等价值的最终结论,有些人认为SEG增加了瘤风险.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 结肠直肠手术 结肠直肠手术
背景情况:
- 整体直肠切除术 (TPC) 是性结肠炎 (UC) 患有发育不良的标准.
- 高风险的手术患者可能不会从广泛的TPC中受益.
- 分段切除术 (SEG) 提供了一个不那么广泛的替代方案.
研究的目的:
- 系统地审查和元分析术后结果,比较UC患者的SEG与TPC.
- 评估SEG和TPC对后续瘤和整体存活率的等价性.
主要方法:
- 八项回顾性研究 (4856名患者) 的系统审查和元分析.
- 从创立到2022年8月搜索全球数据库.
- 计算的几率比率 (ORs) 和危险比率 (HRs);使用纽卡斯尔-太华尺度和GRADE评估质量.
主要成果:
- 在SEG和TPC之间,再手术,Clavien-Dindo III-IV并发症,瘤发展或整体存活率没有显著差异.
- SEG患者年龄较大,并患有更多的并发症.
- 在包含的研究中存在偏差的高风险和证据质量低下.
结论:
- 低质量的证据表明,SEG和TPC之间没有明显的术后结果差异.
- 数据的细节性有限,结果不准确,因此不能断言同等性.
- 在SEG组中,潜在的瘤风险升高和生存率较低的暗示值得进一步调查.
更多相关视频
08:26Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
09:58Transplantation of Adipose Tissue-Derived Stem Cell Sheet to Reduce Leakage After Partial Colectomy in A Rat Model
Published on: August 11, 2018
相关概念视频
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Drugs for Treatment of Ulcerative Colitis in IBD
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures II: Colonoscopy
