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Updated: Jun 3, 2025

Glucose Uptake Measurement and Response to Insulin Stimulation in In Vitro Cultured Human Primary Myotubes
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高葡萄糖抑制O-GlcNAc转移酶转移在早期骨质细胞分化通过改变蛋白质酸酶2A的活动

Heriati Sitosari1,2, Yoko Fukuhara1, Yao Weng1

  • 1Department of Oral Morphology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.

Journal of cellular physiology
|January 13, 2025
PubMed
概括

在骨质细胞分化过程中,O-GlcNAc转移酶 (OGT) 的局部位移,受到蛋白酸酶2A (PP2A) 活性的影响. 这种OGT转位影响关键蛋白质,表明它在骨细胞发育中起着调节作用.

关键词:
在O-GlcNAc转移酶.腺单酸盐激活的蛋白激酶.过高血糖症 (hyperglycemia) 是一种骨质母细胞分化的区别.蛋白酸酶2A是一种蛋白质酸酶.

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