在患有自闭症谱系障碍的人群中使用酒精:叙事系统性审查
William Barber1, Betul Aslan2, Tim Meynen1
1Addictions Department, School of Academic Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
BJPsych open
|January 13, 2025
概括
在患有自闭症谱系障碍 (ASD) 的人群中,酒精使用障碍在一般人群中影响1.6%,在临床环境中影响16.1%. 了解这些关联对于定制干预和政策至关重要.
科学领域:
- 神经发育障碍 神经发育障碍
- 成 药物 药物 药物 药物
- 临床心理学 临床心理学
背景情况:
- 自闭症谱系障碍 (ASD) 中的酒精使用仍未得到充分研究,之前的审查忽视了特定物质的细微差别.
- 了解自闭症患者的酒精使用模式对于推进临床实践和政策至关重要.
- 在非临床自闭症人群中存在对酒精的不同反应,这凸显了对专业研究的需要.
研究的目的:
- 系统地审查临床人群中关于酒精使用和ASD的文献.
- 调查病因,包括生物,心理,社会和环境风险因素.
- 确定与自闭症患者的酒精使用相关的含义,后果和保护因素,并建议未来的研究方向.
主要方法:
- 进行了叙事系统审查.
- 在五个主要数据库中进行了搜索:CINAHL,EMBASE,MEDLINE,PsychINFO和全球健康.
- 在临床样本中包括了专注于酒精使用和ASD的研究 (PROSPERO注册:CRD42023430291).
主要成果:
- 在最终审查中包括了22项研究.
- 在人口登记册中,酒精使用障碍的综合患病率为1.6%,在ASD患者的临床环境中为16.1%.
- 确定的病因风险因素包括年龄,同时发生的疾病,性别和遗传学,对同时发生的酒精使用障碍有10个影响.
结论:
- 新兴趋势表明,未来的研究需要标准化的方法.
- 建议使用经过心理测量验证的仪器和代表性样本.
- 通知政策和改善自闭症个体与同时出现的酒精使用障碍的经验至关重要.
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