根据不同的诊断标准,甘油三糖指数与高血压之间的关联
1Physical Examination Center, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.
International journal of general medicine
|January 13, 2025
概括
三甘油糖 (TyG) 指数是高血压的独立风险因素,较高的TyG水平显著增加了高血压风险. 早期治疗胰岛素抵抗对于预防高血压至关重要.
科学领域:
- 心血管健康 心血管健康
- 代谢综合征是代谢综合征的一种.
- 高血压研究 高血压研究
背景情况:
- 胰岛素抵抗 (IR) 与心血管疾病,包括高血压有关.
- 三甘油糖 (TyG) 指数和TyG-体质指数 (TyG-BMI) 是IR的新兴指标.
- 了解IR标志物与高血压之间的关联对于预防策略至关重要.
研究的目的:
- 为了研究三糖糖 (TyG) 指数和高血压之间的关联.
- 为了检查这种关联跨高血压的不同诊断值.
- 探索身体质量指数 (BMI) 对TyG-高血压关系的潜在影响.
主要方法:
- 分析了从4028名接受职业健康检查的受试者的数据.
- 使用甘油三,禁食血糖和BMI计算TyG和TyG-BMI.
- 后勤回归模型和受限立方线用于评估TyG/TyG-BMI和高血压之间的关联和剂量反应关系,其定义为140/90 mmHg和130/80 mmHg值.
主要成果:
- 较高的TyG指数四分位数与高血压风险增加有显著关联,因数比率在2.87至8.03之间,取决于指数和高血压值.
- 在TyG/TyG-BMI和高血压之间观察到明确的剂量反应关系.
- 这种关联似乎受到BMI的影响,特别是在超重范围 (24.0-27.9 kg/m2) 中.
结论:
- 三甘油糖 (TyG) 指数是跨越各种诊断值的高血压的独立预测指标.
- 在TyG/TyG-BMI和高血压风险之间存在显著的剂量反应关系.
- 管理胰岛素抵抗,如TyG所示,对于预防高血压很重要,BMI可能会改变这种风险.
相关概念视频
Diabetes: Symptoms, Diagnosis, and Complications
500
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
500
Hypertension and Regulation of Blood Pressure
1.9K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
1.9K
Diabetes Mellitus: Type 2 and Gestational
2.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.2K
Alterations in Blood Pressure
1.2K
Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
1.2K
Hypoglycemia and Glucagon
150
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
150
Blood Studies for Cardiovascular System III: Serum Lipid Profile
130
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
130


