全球关于素及其衍生物的研究中新出现的趋势和新进展
Yu Lai1, Huize Zhang1, Xi Chen1
1School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Heliyon
|January 13, 2025
概括
素 (ART) 和其衍生物对于疟疾治疗至关重要,但面临药物耐药性挑战. 这种科学度分析揭示了研究趋势,并确定了抗疟疾药物开发和更广泛的治疗应用的未来方向.
科学领域:
- 药理学和药物化学 药理学和药物化学
- 传染性疾病 传染性疾病
- 药物发现和开发 药物发现和开发
背景情况:
- 素 (ART) 和其衍生物是世卫组织推的抗疟疾药物,具有更广泛的药理潜力.
- 药物耐药性的出现显著阻碍了目前的抗疟疾治疗工作.
- 系统分析对于了解研究趋势和为未来的战略提供信息至关重要.
研究的目的:
- 为了提供一个全面的概述的进步在艺术素 (ART) 和衍生研究.
- 以视觉形式呈现数据,并为后续调查提供见解.
- 确定该领域的研究热点和前沿.
主要方法:
- 系统的文献搜索 Web of Science 核心集合,截至 2023 年 12 月 31 日.
- 使用CiteSpace软件进行科学测量分析.
- 识别国家,机构,作者,期刊,参考文献和关键词的趋势.
主要成果:
- 对12985个数据点的分析表明,全球对ART及其衍生品的科学兴趣很大.
- 长期的国际合作推动了这一研究领域的进展.
- 关键的研究领域包括抗疟药,合成,耐药性和Plasmodium vivax;未来的重点可能包括扩散,氧化应激,途径和机制.
结论:
- 该研究提供了50年来ART和衍生科学的研究发展和趋势的概述.
- 药物药物合成的持续改进对于疗效和成本效益至关重要.
- 对抗药性机制的进一步研究以及对其他疾病的ART衍生物更广泛的治疗潜力是有必要的.
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