在青少年肺结核幸存者中,结核病后的后续症状
C Cesilia1,2, F R Rinawan3, P Santoso4
1Division of Respirology, Department of Child Health, Faculty of Medicine, Universitas Padjadjaran/Dr Hasan Sadikin General Hospital, Bandung, Indonesia.
IJTLD open
|January 13, 2025
概括
药物敏感 (DS) 和耐药 (DR) 肺结核 (PTB) 的青少年幸存者经历了不同的长期肺部问题. 治疗后对PTB幸存者进行监测至关重要,特别是对于青少年来说.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 青少年医学 青少年医学
背景情况:
- 肺结核 (PTB) 在青少年幸存者中可能导致持续的临床症状和肺部后果.
- 区分药物敏感 (DS) 和耐药 (DR) PTB之间的结果对于有针对性的随访至关重要.
- 在PTB幸存的青少年中长期肺部连续症需要进一步调查.
研究的目的:
- 为了比较持续的临床症状,胸部X射线 (CXR),螺旋计和心声扫描在DS-PTB的青少年幸存者与DR-PTB的发现.
- 在青少年PTB幸存者中识别与肺部连续症相关的危险因素.
主要方法:
- 对52名青少年PTB幸存者的回顾性队列研究.
- 在DS-TB和DR-TB组之间比较持久的临床症状,CXR,螺旋计和心声学.
- 统计分析包括千二测试,物流回归和多面拉什分析,以获得CXR评级者之间的一致性.
主要成果:
- DS-TB幸存者有更持久的临床症状,而DR-TB幸存者显示出更高的CXR和螺旋测量异常率.
- 心声图显示,在两组患者中,肺高血压的可能性很低.
- 伴随性疾病在青少年PTB幸存者中增加了1.5倍的肺部继发症风险.
结论:
- 在DS和DR-PTB的青少年幸存者中存在肺部连续病.
- 在PTB治疗完成后持续监测对所有青少年幸存者至关重要,特别是那些患有并发症的青少年.
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