选择重复的焦点和旋转激活模式,这些模式最有可能成为心房的来源
Ben J M Hermans1,2, Ozan Özgül1, Michael Wolf3
1Department of Physiology, Cardiovascular Research Institute Maastricht (CARIM), University Maastricht, Maastricht, the Netherlands.
Journal of molecular and cellular cardiology plus
|January 13, 2025
概括
这项研究引入了一种新的方法,通过评估模式的重复性和引力能力来识别心房动 (AF) 的来源. 这种技术有助于更准确地确定AF驱动器,改进了切除策略.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗成像医学成像
背景情况:
- 前庭动 (AF) 除通常针对重复的焦点和旋转激活模式.
- 目前的方法缺乏明确的证据,证明所有目标模式都是真正的AF源.
- 确定精确的AF驱动器对于有效的消融疗法至关重要.
研究的目的:
- 开发和验证一种用于检测和排列AF激活模式的新方法.
- 为了区分真正的AF源与仅仅基于引力能力的重复模式.
- 增强选择最有可能成为AF源的废弃目标.
主要方法:
- 在13名经过过切除的持久性AF患者中,对高密度的双心房顺序映射进行了回顾性分析.
- 使用单极电图注释检测重复的焦点和旋转模式.
- 评估已识别的模式的空间稳定性和引能力.
主要成果:
- 对459个录音的分析揭示了131个重复的焦点和56个旋转模式.
- 焦点模式的重复性明显高于旋转模式 (p < 0.001).
- 一个新的值在7名患者中确定了10个可能的AF源部位,主要在右心房和肺静脉中.
结论:
- 一种新的技术有效地根据重复性和引入性对AF激活模式进行排名.
- 只有少数重复模式似乎是真正的AF源,能够引入它们的附近.
- 这种方法提供了一种更可靠的方式来选择最佳的消融目标,持续AF.
更多相关视频
08:10Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
1.6K
10:17Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
Published on: April 11, 2025
388
相关概念视频
Disturbances in Heart Rhythm
894
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
894
Mechanism of Cardiac Arrhythmias
885
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
885
